Genetic Laboratory Helix Lab is a unique type of laboratory in Serbia where, with the help of the most contemporary international methods, you can carry out some of the DNA analysis you need. In a precise, reliable and speedy manner.

Nutrigenetics

By recognizing risks at an early stage, followed by an
appropriate diet and lifestyle the ageing process can be
slowed down and a number     of hereditary diseases can be
prevented such as obesity, osteoporosis, thrombosis,
cardiovascular diseases…

The connection between genes and diet, i.e. their mutual influence is the
basis of researching Nutrigenetics. This scientific field possibly
illustrates best that a human being is a unique and unrepeatable individual,
because the basic cause of physical differences amongst human beings
are genetic differences.
Following that analysis, what can be beneficial for the organism of one
human being, doesn’t necessarily have to have the same impact on another.
We all derive energy and basic materials from food, however, people
who have the same diet still look different, they react differently to the
consumed substances and release toxins from the body, they are not
equally prone to illnesses, i.e. medicine as well, and finally, they
age differently.
That is the very reason why risks should be discovered at an early stage,
after which with an appropriate diet and lifestyle the aging process of
the organism can be slowed down and numerous hereditary diseases can
be prevented – obesity, osteoporosis, thrombosis, cardiovascular
diseases, certain types of cancer…
Molecular-biological methods which are used in the Helix laboratory,
provide us with the opportunity to discover genetic modifications,
which cause various reactions to consumed vitamins and minerals.
Depending on the results an appropriate diet is proposed which will
correspond to your genetic profile.

In our laboratory the following gene groups are analyzed:

•    Genes responsible for the metabolism of fat (APOB, APOE,
APO C3, CETP, LPL, NOS3)
Analyzing the polyphormisms of these genes can establish whether you
have an increased risk of cardiovascular diseases

•    Genes responsible for obesity (ADR 2B, ADRB1, ADRB2,
ADRB3, PPARG)
The first four listed genes code proteins (transfer the genetic message from
DNA to proteins), which inhibit insulin secretion, participate in
the decomposition and storaging of fats, regulate blood pressure and speed
of blood flow. The PPARG gene is responsible for insulin resistance.
Modifications on any of these genes can be the cause of obesity, which can
be kept under control with an appropriate diet.

•    Genes responsible for the metabolism of homocysteines (CBS,
MTHFR, MTR, MTRR)
Homocysteine is an amino acid which is normally found in all cells of the body.
It has been established that an increased level of homocysteine is connected
with the risk of coronary arteries disease, strokes and thromboembolia for
people with normal cholesterol levels. A genetic deficit of cystation ß synthesis
is the cause of an incredibly high level of homocysteines

•    Genes responsible for inflammatory processes (IL-6, TNF a)
Testing these genes can show us what the inflammatory defense of our
organism is like, i.e. whether we are prone to various inflammatory processes.

•    Genes responsible for the metabolism of bones and osteoporosis
(VDR, COLI, A1)
Osteoporosis is a metabolical illness of the bones which manifests itself in
decreased bone mass during aging and menopause. After both women and men turn thirty, the density of bone mass decreases, whereby they become fragile
and easily breakable. Our analysis can uncover modifications in the genes
responsible for healthy bones, and the actual illness itself can be
slowed down with an appropriate diet and lifestyle.

The Risk Factors Are:

•    Positive family anamnesis
•    Racial affiliation
•    Women who never gave birth to a child
•    Low height and low weight
•    Early menopause
•    Diet factors
•    Lifestyle

•    Genes responsible for the activity of antioxidants and detoxification
(MnSOD, SOD3, GSTP1, GSTM1, GSTT1)
Genotoxic agents, such as UV radiation or chemical agents can lead to the
creation of free radicals which damage cells. An organism defends itself from
free radicals with antioxidants. However, genetic mutations included in the
metabolism of antioxidants can lead to a decreased capability of the organism
to eliminate free radicals, which can cause premature aging, heart diseases,    chronic inflammations and development of cancer. If genetic predispositions are discovered on time, with a targeted intake of antioxidants found in food,
the genetic deficiency can be partially compensated.